Cd177^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Cd177^{tm1(KOMP)Vlcg}
• Name: CD177 antigen; targeted mutation 1, Velocigene
• MGI ID: MGI:4415421
• Gene: Cd177 Location: Chr7:24443408-24459736 bp, - strand Genetic Position: Chr7, 12.58 cM
• Alliance: Cd177^{tm1(KOMP)Vlcg} page
• IMPC: Cd177 gene page

Mutation origin

• Mutant Cell Lines: 12120A-B11, 12120A-E8, 12120A-F2, 12120A-G10
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 16087bp between positions 24443438-24459524 of Chromosome 7 (Build GRCm39). The lacZ anf floxed neomycin resistance cassette replaced the coding sequence. FACS analysis confirmed the absence of protein on blood and bone marrow cells. (J:136110, J:225335)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd177 Mutation: 56 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)