C1qtnf9^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: C1qtnf9^{tm1(KOMP)Vlcg}
• Name: C1q and tumor necrosis factor related protein 9; targeted mutation 1, Velocigene
• MGI ID: MGI:4415477
• Synonyms: CTRP9 KO
• Gene: C1qtnf9 Location: Chr14:61005583-61018318 bp, + strand Genetic Position: Chr14, 31.93 cM
• Alliance: C1qtnf9^{tm1(KOMP)Vlcg} page
• IMPC: C1qtnf9 gene page

Mutation origin

• Mutant Cell Lines: 12588A-C6, 12588A-C12, 12588A-E11, 12588A-G1, 12588A-H11
• Germline Transmission: Earliest citation of germline transmission: J:212299
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 7725bp between positions 61009749-61017473 of Chromosome 14 (Build GRCm39). A lacZ and floxed neomycin resistance cassette replaced exon 3. Western blot analysis confirmed absence of detectable protein in white adipose tissue lysates and serum from homozygous mutant mice. (J:136110, J:212299)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any C1qtnf9 Mutation: 20 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 7 reference(s)