Jakmip1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Jakmip1^{tm1(KOMP)Vlcg}
• Name: janus kinase and microtubule interacting protein 1; targeted mutation 1, Velocigene
• MGI ID: MGI:4415497
• Gene: Jakmip1 Location: Chr5:37185679-37307951 bp, + strand Genetic Position: Chr5, 19.66 cM
• Alliance: Jakmip1^{tm1(KOMP)Vlcg} page
• IMPC: Jakmip1 gene page

Mutation origin

• Mutant Cell Lines: 12661A-D9, 12661A-F7
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 21943bp between positions 37242717-37264659 of Chromosome 5 (Build GRCm39). Coding exons 2-8 were replaced with a lacZ-neo cassette. (J:136110, J:228732)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Jakmip1 Mutation: 55 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)