Nkapl^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Nkapl^{tm1(KOMP)Vlcg}
• Name: NFKB activating protein-like; targeted mutation 1, Velocigene
• MGI ID: MGI:4415546
• Gene: Nkapl Location: Chr13:21651217-21652671 bp, - strand Genetic Position: Chr13, 7.81 cM, cytoband A3.1
• Alliance: Nkapl^{tm1(KOMP)Vlcg} page
• IMPC: Nkapl gene page

Mutation origin

• Mutant Cell Lines: 12856A-B1, 12856A-D12
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1191bp between positions 21651418-21652608 of Chromosome 13 (Build GRCm39). Western blot analysis confirmed the absence of protein expression in the testis. (J:136110, J:229252)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Nkapl Mutation: 15 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)