Tg(Hes7-cre)1Kag
Transgene Detail

Summary

• Symbol: Tg(Hes7-cre)1Kag
• Name: transgene insertion 1, Ryoichiro Kageyama
• MGI ID: MGI:4415616
• Synonyms: Hes7-Cre (Acc. No. CDB0551T)
• Transgene: Tg(Hes7-cre)1Kag Location: unknown
• Alliance: Tg(Hes7-cre)1Kag page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Hes7-cre)1Kag expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Hes7

• Mutation details: Nuclear localizing Cre recombinase is expressed under control of a 5.4-kb genomic DNA fragment containing the Hes7 (hairy and enhancer of split 7 (Drosophila)) promoter. Cre mRNA is expressed in the presomitic mesoderm (PSM) of the E10.5 embryo, and its expression appears to oscillate. In doubly transgenic embryos bearing this transgene and a lacZ reporter transgene, X-gal staining is observed throughout the PSM and in the somites and their derivatives at E7.5-E10.5. (J:124102)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hes7 (species not specified) Summary of all recombinase alleles driven by Hes7. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

3 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:124102 Niwa Y, et al., The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock. Dev Cell. 2007 Aug;13(2):298-304
• All: 3 reference(s)