Dnai1^tm1.2Leo
Targeted Allele Detail

Summary

• Symbol: Dnai1^tm1.2Leo
• Name: dynein axonemal intermediate chain 1; targeted mutation 1.2, Lawrence E Ostrowski
• MGI ID: MGI:4415703
• Gene: Dnai1 Location: Chr4:41569775-41638158 bp, + strand Genetic Position: Chr4, 21.75 cM
• Alliance: Dnai1^tm1.2Leo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154976
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 17 and 18 were removed by cre mediated recombination. (J:155730)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnai1 Mutation: 47 strains or lines available

References

• Original: J:154976 Jacquet BV, et al., FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain. Development. 2009 Dec;136(23):4021-31
• All: 5 reference(s)