Tg(CAG-flpe)37Ito
Transgene Detail

Summary

• Symbol: Tg(CAG-flpe)37Ito
• Name: transgene insertion 37, Shigeyoshi Itohara
• MGI ID: MGI:4415709
• Synonyms: CAG-FLPe deleter, Tg-CAG_FLPe37
• Transgene: Tg(CAG-flpe)37Ito Location: unknown
• Alliance: Tg(CAG-flpe)37Ito page

Transgene origin

• Strain of Origin: C57BL/6JJcl

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(CAG-flpe)37Ito expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  chicken	CAG

• Mutation details: The CAG promoter (chicken beta-actin promoter with CMV enhancers) was used to drive expression of a gene encoding nuclear localized FLPe recombinase. Five founder lines were established (lines 16, 32, 36, 37 and 41), of which lines 16, 32 and 36 exhibited 100% recombination when crossed to a mouse bearing a frt-flanked cassette; 10/11 mice of line 37 showed recombination. Mosaicism was noted in 2/9 of line 16 and in 1/8 of line 32 double transgenic mice. (J:108559)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:108559 Kanki H, et al., High-efficiency CAG-FLPe deleter mice in C57BL/6J background. Exp Anim. 2006 Apr;55(2):137-41
• All: 16 reference(s)