Wwox^tm1Mald
Targeted Allele Detail

Summary

• Symbol: Wwox^tm1Mald
• Name: WW domain-containing oxidoreductase; targeted mutation 1, Marcelo Aldaz
• MGI ID: MGI:4415791
• Synonyms: Wwox^flox
• Gene: Wwox Location: Chr8:115166395-116079447 bp, + strand Genetic Position: Chr8, 60.99 cM, cytoband E1
• Alliance: Wwox^tm1Mald page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155406
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: An frt flanked neo cassette with a 5' loxP site was inserted upstream of exon 1 and an additional loxP site was inserted downstream of the exon. (J:155406)

Generation of the Wwox^tm1Mald allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wwox Mutation: 59 strains or lines available

References

• Original: J:155406 Ludes-Meyers JH, et al., Generation and characterization of mice carrying a conditional allele of the Wwox tumor suppressor gene. PLoS One. 2009;4(11):e7775
• All: 6 reference(s)