Wwox^tm1.1Mald
Targeted Allele Detail

Summary

• Symbol: Wwox^tm1.1Mald
• Name: WW domain-containing oxidoreductase; targeted mutation 1.1, Marcelo Aldaz
• MGI ID: MGI:4415792
• Synonyms: Wwox^deltaCre
• Gene: Wwox Location: Chr8:115166395-116079447 bp, + strand Genetic Position: Chr8, 60.99 cM, cytoband E1
• Alliance: Wwox^tm1.1Mald page

Reduced growth of Wwox^tm1.1Mald/Wwox^tm1.1Mald newborns

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155406
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Exon 1 was removed by cre mediated recombination. (J:155406)

Generation of the Wwox^tm1.1Mald allele

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wwox Mutation: 59 strains or lines available

References

• Original: J:155406 Ludes-Meyers JH, et al., Generation and characterization of mice carrying a conditional allele of the Wwox tumor suppressor gene. PLoS One. 2009;4(11):e7775
• All: 1 reference(s)