Prkci^tm1.1Kido
Targeted Allele Detail

Summary

• Symbol: Prkci^tm1.1Kido
• Name: protein kinase C, iota; targeted mutation 1.1, Yoshiaki Kido
• MGI ID: MGI:4417855
• Synonyms: aPKClambda^deleted
• Gene: Prkci Location: Chr3:31049893-31106889 bp, + strand Genetic Position: Chr3, 14.65 cM
• Alliance: Prkci^tm1.1Kido page

Focal segmental glomerulosclerosis in Prkci^tm1Kido/Prkci^tm1.1Kido Tg(Nphs1-cre)33Mska/0 mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154910
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 5 has been deleted. (J:154910)

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkci Mutation: 69 strains or lines available

References

• Original: J:154910 Sugiyama Y, et al., A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56
• All: 3 reference(s)