Tg(KRT14-COL7A1)1Shzu
Transgene Detail

Summary

• Symbol: Tg(KRT14-COL7A1)1Shzu
• Name: transgene insertion 1, Hiroshi Shimizu
• MGI ID: MGI:4417875
• Synonyms: COL7^K14-h+
• Transgene: Tg(KRT14-COL7A1)1Shzu Location: unknown
• Alliance: Tg(KRT14-COL7A1)1Shzu page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-COL7A1)1Shzu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  COL7A1 (1294)

  Col7a1

  (MGI:88462)

• Mutation details: The human promoter was used to drive epidermis-specific expression of the human cDNA. Several lines were created with most robust expressing line was selected as the representative line. No line numbers given. (J:155326)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:155326 Ito K, et al., Keratinocyte-/fibroblast-targeted rescue of Col7a1-disrupted mice and generation of an exact dystrophic epidermolysis bullosa model using a human COL7A1 mutation. Am J Pathol. 2009 Dec;175(6):2508-17
• All: 2 reference(s)