Tg(CMV-COL7A1)1Shzu
Transgene Detail

Summary

• Symbol: Tg(CMV-COL7A1)1Shzu
• Name: transgene insertion 1, Hiroshi Shimizu
• MGI ID: MGI:4417879
• Synonyms: COL7^CMV-h+
• Transgene: Tg(CMV-COL7A1)1Shzu Location: unknown
• Alliance: Tg(CMV-COL7A1)1Shzu page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CMV-COL7A1)1Shzu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  COL7A1 (1294)

  Col7a1

  (MGI:88462)

• Mutation details: The CMV promoter was used to drive ubiquitous expression of the human cDNA. Several lines were created with most robust expressing line was selected as the representative line. No line numbers given. (J:155326)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:155326 Ito K, et al., Keratinocyte-/fibroblast-targeted rescue of Col7a1-disrupted mice and generation of an exact dystrophic epidermolysis bullosa model using a human COL7A1 mutation. Am J Pathol. 2009 Dec;175(6):2508-17
• All: 2 reference(s)