Tg(Krt14-Fyn)AJsey
Transgene Detail

Summary

• Symbol: Tg(Krt14-Fyn)AJsey
• Name: transgene insertion A, John Seykora
• MGI ID: MGI:4417888
• Synonyms: K14-Fyn
• Transgene: Tg(Krt14-Fyn)AJsey Location: unknown
• Alliance: Tg(Krt14-Fyn)AJsey page

Transgene origin

• Strain of Origin: C57BL/6 x CBA

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Krt14-Fyn)AJsey expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fyn (MGI:95602)

• Mutation details: Murine Fyn gene was inserted downstream of the human keratin 14 promoter. Line A was used in the study. Western Blot confirmed transgene expression in the skin. (J:118155)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:118155 Li W, et al., Srcasm corrects Fyn-induced epidermal hyperplasia by kinase down-regulation. J Biol Chem. 2007 Jan 12;282(2):1161-9
• All: 1 reference(s)