Ntsr1^tm1Pang
Targeted Allele Detail

Summary

• Symbol: Ntsr1^tm1Pang
• Name: neurotensin receptor 1; targeted mutation 1, Zhen Pang
• MGI ID: MGI:4418203
• Gene: Ntsr1 Location: Chr2:180141769-180186772 bp, + strand Genetic Position: Chr2, 103.04 cM, cytoband H1-H4
• Alliance: Ntsr1^tm1Pang page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155775
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Homologous recombination resulted in deletion of 1.4 kb of genomic sequence including the exon that encodes the N-terminal 238 amino acids. (J:155775)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ntsr1 Mutation: 31 strains or lines available

References

• Original: J:155775 Feifel D, et al., Sensorimotor gating in neurotensin-1 receptor null mice. Neuropharmacology. 2010 Jan;58(1):173-8
• All: 1 reference(s)