Tg(CAG-Spltc1)6FAmcc
Transgene Detail

Summary

• Symbol: Tg(CAG-Spltc1)6FAmcc
• Name: transgene insertion 6F, Alexander McCampbell
• MGI ID: MGI:4418352
• Synonyms: SPTLC1^WT
• Transgene: Tg(CAG-Spltc1)6FAmcc Location: unknown
• Alliance: Tg(CAG-Spltc1)6FAmcc page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Spltc1)6FAmcc expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  hamster, Chinese	Sptlc1 (100689326)

• Mutation details: The CAG promoter drives ubiquitous expression of a Chinese hamster cDNA. Three lines were created (lines 6B, 6F, and 6H) with line 6F selected as the representative line. (J:106812)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:106812 McCampbell A, et al., Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy. Hum Mol Genet. 2005 Nov 15;14(22):3507-21
• All: 4 reference(s)