Ehmt1tm1.2Tara
Targeted Allele Detail
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Symbol: |
Ehmt1tm1.2Tara |
Name: |
euchromatic histone methyltransferase 1; targeted mutation 1.2, Alexander Tarakhovsky |
MGI ID: |
MGI:4418565 |
Gene: |
Ehmt1 Location: Chr2:24680781-24809658 bp, - strand Genetic Position: Chr2, 16.73 cM
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Alliance: |
Ehmt1tm1.2Tara page
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Germline Transmission: |
Earliest citation of germline transmission:
J:155739
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Parent Cell Line: |
E14.1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 23 was floxed and an FRT-flanked neo cassette was inserted into intron 23 via homologous recombination. The selection cassette and exon 23 were removed by flp and cre mediated recombination, respectively. Cre-mediated recombination results in out-of-frame splicing and nonsense mediated decay of the mutant transcript.
(J:155739)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ehmt1 Mutation: |
91 strains or lines available
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Original: |
J:155739 Schaefer A, et al., Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex. Neuron. 2009 Dec 10;64(5):678-91 |
All: |
1 reference(s) |
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