Adamts9^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Adamts9^tm1Dgen
• Name: ADAM metallopeptidase with thrombospondin type 1 motif 9; targeted mutation 1, Deltagen
• MGI ID: MGI:4418751
• Synonyms: Adamts9^-, Adamts9^ko, Adamts9^LacZ
• Gene: Adamts9 Location: Chr6:92749680-92920473 bp, - strand Genetic Position: Chr6, 41.41 cM
• Alliance: Adamts9^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:156090
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: 134 nucleotides of exon 12 encoding contiguous portions of the disintegrin-like domain and first thrombospondin type-1 repeat were deleted and replaced with an IRES-lacZ-Neomycin resistance cassette (personal communication). (J:156090)

Expression

In Mice Carrying this Mutation:

17 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adamts9 Mutation: 90 strains or lines available

References

• Original: J:155754 McCulloch DR, et al., ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression. Dev Cell. 2009 Nov;17(5):687-98
• All: 12 reference(s)