Aars2tm1(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Aars2tm1(KOMP)Wtsi |
Name: |
alanyl-tRNA synthetase 2, mitochondrial; targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:4419134 |
Gene: |
Aars2 Location: Chr17:45817767-45831769 bp, + strand Genetic Position: Chr17, 22.51 cM
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Alliance: |
Aars2tm1(KOMP)Wtsi page
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IMPC: |
Aars2 gene page |
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Mutant Cell Lines: |
EPD0406_3_A04, EPD0406_3_B03, EPD0406_3_C02, EPD0406_3_C04, EPD0406_3_D02, EPD0406_3_D03, EPD0406_3_D04, EPD0406_3_E01, EPD0406_3_E04, EPD0406_3_F03, EPD0406_3_F04, EPD0406_3_G02, EPD0406_3_G03, EPD0406_3_H01, EPD0406_3_H03 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 6330 starting at position 45819340 and ending at position 45825670 of Chromosome 17 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site.
(J:148605, J:173534)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
All: |
5 reference(s) |
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