Slc45a2^uw-5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Slc45a2^uw-5Btlr
• Name: solute carrier family 45, member 2; underwhite 5 Bruce Beutler
• MGI ID: MGI:4420315
• Synonyms: june gloom, Slc45a2^m5Btlr
• Gene: Slc45a2 Location: Chr15:11000807-11029319 bp, + strand Genetic Position: Chr15, 5.4 cM
• Alliance: Slc45a2^uw-5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation, discovered among G3 progeny of an ENU treated mouse, comprises a T to C transition at nucleotide position 22723 (Genbank genomic region NC_000081 for linear genomic sequence of Slc45a2), in the fifth of the gene's seven exons. This corresponds to nucleotide 1228 of the transcript and is predicted to result in replacement of serine by proline at amino acid position 378, in the eighth transmembrane domain of the protein (S378P). (J:86521, J:156313)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc45a2 Mutation: 55 strains or lines available

References

• Original: J:156313 Du X, et al., June gloom is an allele of Slc45a2 and displays pigmentation defects. MGI Direct Data Submission. 2010
• All: 4 reference(s)