Tg(tetO-LRRK2*)D10Cai
Transgene Detail
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| Symbol: |
Tg(tetO-LRRK2*)D10Cai |
| Name: |
transgene insertion D10, Huaibin Cai |
| MGI ID: |
MGI:4420818 |
| Synonyms: |
tetO-KD |
| Transgene: |
Tg(tetO-LRRK2*)D10Cai Location: unknown
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| Alliance: |
Tg(tetO-LRRK2*)D10Cai page
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Mutation details: A transgenic vector was generated encoding the C-terminal hemagglutinin (HA)-tagged human LRRK2 gene with complete deletion of the kinase domain (deletion of residues 1187 to 2102) under control of a tetO promoter. The construct was microinjected into fertilized oocytes. Line D10 was analyzed further.
(J:156512)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:156512 Lin X, et al., Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein. Neuron. 2009 Dec 24;64(6):807-27 |
| All: |
1 reference(s) |
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Analysis Tools
