Jag1^Ndr
Chemically induced Allele Detail

Summary

• Symbol: Jag1^Ndr
• Name: jagged 1; Nodder
• MGI ID: MGI:4420947
• Synonyms: Jagged1^Ndr
• Gene: Jag1 Location: Chr2:136923371-136958440 bp, - strand
• Alliance: Jag1^Ndr page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A single base-pair mutation is present in the extracellular domain. Sequencing indicated a histidine-to-glutamine change at position 268 (H268Q) in the second EGF-like repeat of the extracellular domain. (J:156172, J:277896)

Disease models

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Jag1 Mutation: 78 strains or lines available

References

• Original: J:156172 Marklund U, et al., Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression. Development. 2010 Feb;137(3):437-45
• All: 6 reference(s)