Ncdn^tm1.1Mfla
Targeted Allele Detail

Summary

• Symbol: Ncdn^tm1.1Mfla
• Name: neurochondrin; targeted mutation 1.1, Marc Flajolet
• MGI ID: MGI:4420954
• Gene: Ncdn Location: Chr4:126637548-126647203 bp, - strand Genetic Position: Chr4, 60.93 cM, cytoband D2.1
• Alliance: Ncdn^tm1.1Mfla page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155805
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3 and 4 were floxed, and an FRT flanked neo cassette was inserted within intron 3 by homologous recombination. The neo cassette was removed by flp meditated recombination leaving exons 3 and 4 floxed. (J:155805)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ncdn Mutation: 41 strains or lines available

References

• Original: J:155805 Wang H, et al., Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signaling. Science. 2009 Dec 11;326(5959):1554-7
• All: 2 reference(s)