Gadd45gip1^tm2Kong
Targeted Allele Detail

Summary

• Symbol: Gadd45gip1^tm2Kong
• Name: growth arrest and DNA-damage-inducible, gamma interacting protein 1; targeted mutation 2, Young-Yun Kong
• MGI ID: MGI:4420970
• Synonyms: Crif1^flox
• Gene: Gadd45gip1 Location: Chr8:85558911-85562111 bp, + strand Genetic Position: Chr8, 41.19 cM
• Alliance: Gadd45gip1^tm2Kong page

Abnormal small intestine morphogenesis in Gadd45gip1^tm2Kong/Gadd45gip1^tm2Kong Tg(Vil1-cre)997Gum/0 embryos

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:156583
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Intragenic deletion
• Mutation details: LoxP sites were inserted around exon 2 and an frt flanked neo cassette was inserted downstream of exon 2 via homologous recombination. (J:156583)

Disease models

Expression

In Mice Carrying this Mutation:	46 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gadd45gip1 Mutation: 19 strains or lines available

References

• Original: J:156583 Kwon MC, et al., Crif1 is a novel transcriptional coactivator of STAT3. EMBO J. 2008 Feb 20;27(4):642-53
• All: 21 reference(s)