Tg(tetO-SNCA)1Cai
Transgene Detail

Summary

• Symbol: Tg(tetO-SNCA)1Cai
• Name: transgene insertion 1, Huaibin Cai
• MGI ID: MGI:4420977
• Synonyms: alpha-syn WT
• Transgene: Tg(tetO-SNCA)1Cai Location: unknown
• Alliance: Tg(tetO-SNCA)1Cai page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-SNCA)1Cai expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SNCA (6622)

  Snca	(MGI:1277151)

• Mutation details: A transgenic vector was generated encoding the human SNCA gene under the control of a tetO promoter. The construct was microinjected into fertilized oocytes, and a line of mice was established. (J:156512)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:156512 Lin X, et al., Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein. Neuron. 2009 Dec 24;64(6):807-27
• All: 2 reference(s)