Ift172^tm1.1Rama
Targeted Allele Detail

Summary

• Symbol: Ift172^tm1.1Rama
• Name: intraflagellar transport 172; targeted mutation 1.1, Richard A Maurer
• MGI ID: MGI:4420979
• Synonyms: Ift172^f, Ift172^flox
• Gene: Ift172 Location: Chr5:31410623-31448458 bp, - strand Genetic Position: Chr5, 17.27 cM, cytoband B1
• Alliance: Ift172^tm1.1Rama page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:156426
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. Flp mediated recombination removed the neo cassette leaving exons 2 and 3 floxed. (J:156426)

Disease models

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ift172 Mutation: 75 strains or lines available

References

• Original: J:156426 Howard PW, et al., Generation of mice with a conditional allele for Ift172. Transgenic Res. 2010 Feb;19(1):121-6
• All: 4 reference(s)