Pcdha^tm7.1Tyag
Targeted Allele Detail

Summary

• Symbol: Pcdha^tm7.1Tyag
• Name: protocadherin alpha cluster; targeted mutation 7.1, Takeshi Yagi
• MGI ID: MGI:4421010
• Synonyms: CNR GRv11dneo, Pcdha^11R
• Gene: Pcdha Location: unknown Genetic Position: Chr18, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:156323
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutation: Insertion Mutation details: Exon a11 was replaced with a cassette containing a GAP43 N-terminal peptide (MLCCMRRTK), an HcRed protein, a floxed neo cassette, an IRES sequence, a Kozak sequence, and exon a11. Cre mediated recombination removed the neo cassette. (J:156323)

Generation of the Pcdha^tm7.1Tyag allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pcdha Mutation: 52 strains or lines available

References

• Original: J:156323 Noguchi Y, et al., Total expression and dual gene-regulatory mechanisms maintained in deletions and duplications of the Pcdha cluster. J Biol Chem. 2009 Nov 13;284(46):32002-14
• All: 1 reference(s)