Slc20a1^tm1.2Cmg
Targeted Allele Detail

Summary

• Symbol: Slc20a1^tm1.2Cmg
• Name: solute carrier family 20, member 1; targeted mutation 1.2, Cecilia M Giachelli
• MGI ID: MGI:4421036
• Synonyms: PiT-1^deltae3,4
• Gene: Slc20a1 Location: Chr2:129040684-129053536 bp, + strand Genetic Position: Chr2, 62.79 cM
• Alliance: Slc20a1^tm1.2Cmg page

Slc20a1^tm1.2Cmg/Slc20a1^tm1.2Cmg embryos are developmentally delayed and anemic and yolk sacs lack mature vasculature

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:156027
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Cre mediated recombination removed exons 3 and 4. The absence of transcripts containing exon 2 was confirmed by semi-quantitative RT-PCR analysis on E11.5 embryo extracts. (J:156027)

Generation of the Slc20a1^tm1.1Cmg and Slc20a1^tm1.2Cmg alleles

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc20a1 Mutation: 36 strains or lines available

References

• Original: J:156027 Festing MH, et al., Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1. Genesis. 2009 Dec;47(12):858-63
• All: 1 reference(s)