Lmo4^tm1Gan
Targeted Allele Detail

Summary

• Symbol: Lmo4^tm1Gan
• Name: LIM domain only 4; targeted mutation 1, Lin Gan
• MGI ID: MGI:4421413
• Synonyms: Lmo4^lacZ
• Gene: Lmo4 Location: Chr3:143894291-143910981 bp, - strand Genetic Position: Chr3, 68.61 cM
• Alliance: Lmo4^tm1Gan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:156733
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 and part of intron 2 were replaced with a lacZ gene. X-gal staining confirmed lacZ expression in E9.5 embryos. Immunolabeling confirmed the absence of endogenous protein expression at E10.5 in the ear. (J:156733)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lmo4 Mutation: 9 strains or lines available

References

• Original: J:156733 Deng M, et al., Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear. Dev Biol. 2010 Feb 1;338(1):38-49
• All: 4 reference(s)