Tg(KRT14-EGFP/Actb)50Efu
Transgene Detail

Summary

• Symbol: Tg(KRT14-EGFP/Actb)50Efu
• Name: transgene insertion 50, Elaine Fuchs
• MGI ID: MGI:4421514
• Synonyms: K14-GFP-actin
• Transgene: Tg(KRT14-EGFP/Actb)50Efu Location: unknown
• Alliance: Tg(KRT14-EGFP/Actb)50Efu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-EGFP/Actb)50Efu expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Actb (MGI:87904)

• Mutation details: The construct contained a 2.1 kb fragment of the human KRT14 promoter, rabbit beta-globin intron, and EGFP/beta-actin cDNA. followed by KRT14 3' untranslated and polyadenylation sequences. Seven founders were obtained and 2 lines were propagated. Transgene expression occurs in mitotically active epidermal cells.For founder line 50, around 2-3% of total actin was made up of transgenic GFP-actin. (J:156846)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:156846 Vaezi A, et al., Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium. Dev Cell. 2002 Sep;3(3):367-81
• All: 22 reference(s)