Hira^{Tn(mm-DTT-3XSstop)L.1Ddra}
Transposon induced Allele Detail

Summary

• Symbol: Hira^{Tn(mm-DTT-3XSstop)L.1Ddra}
• Name: histone cell cycle regulator; transposon insertion L.1, Dubravka Drabek
• MGI ID: MGI:4421559
• Gene: Hira Location: Chr16:18695787-18789059 bp, + strand Genetic Position: Chr16, 11.69 cM, cytoband A-B1
• Alliance: Hira^{Tn(mm-DTT-3XSstop)L.1Ddra} page

Mutation origin

• Strain of Origin: mixed

Mutation description

• Allele Type: Transposon induced (Not Specified)
• Mutation: Transposon insertion
• Mutation details: The Minos-specific double-transposon trap with 3 STOP codons inserted into the first intron. RT-PCR confirmed the expression of a truncated fusion transcript. This allele was generated by crossing Hist1h1t^{tm1.1(mm)Ddra} or Tg(Hist1h1t-mm)ADdra mice with TgTn(mm-DTT-3XSstop)LDdra mice. (J:156413)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hira Mutation: 74 strains or lines available

References

• Original: J:156413 de Wit T, et al., Tagged mutagenesis by efficient Minos-based germ line transposition. Mol Cell Biol. 2010 Jan;30(1):68-77
• All: 1 reference(s)