Fat2^tm1Anjm
Targeted Allele Detail

Summary

• Symbol: Fat2^tm1Anjm
• Name: FAT atypical cadherin 2; targeted mutation 1, Andrew N J McKenzie
• MGI ID: MGI:4421682
• Gene: Fat2 Location: Chr11:55141435-55227390 bp, - strand Genetic Position: Chr11, 32.5 cM
• Alliance: Fat2^tm1Anjm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155870
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A loxP site and Neo cassette were inserted into the first exon of the Fat2 gene by homologous recombination. (J:155870)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fat2 Mutation: 227 strains or lines available

References

• Original: J:155870 Barlow JL, et al., A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome. Nat Med. 2010 Jan;16(1):59-66
• All: 1 reference(s)