Cd300lf^tm1Gne
Targeted Allele Detail

Summary

• Symbol: Cd300lf^tm1Gne
• Name: CD300 molecule like family member F; targeted mutation 1, Genentech
• MGI ID: MGI:4421781
• Synonyms: CLM-1^-
• Gene: Cd300lf Location: Chr11:115007040-115024818 bp, - strand Genetic Position: Chr11, 80.59 cM
• Alliance: Cd300lf^tm1Gne page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:156819
• Parent Cell Line: C2 (Nagy) (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on bone marrow-derived dendritic cells. (J:156819)

Generation of the Cd300lf^tm1Gne allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd300lf Mutation: 21 strains or lines available

References

• Original: J:156819 Xi H, et al., Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1. J Exp Med. 2010 Jan 18;207(1):7-16, S1-5
• All: 8 reference(s)