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Ccnd1tm3Pisc
Targeted Allele Detail
Summary
Symbol: Ccnd1tm3Pisc
Name: cyclin D1; targeted mutation 3, Piotr Sicinski
MGI ID: MGI:4421800
Synonyms: CcndNtag
Gene: Ccnd1  Location: Chr7:144483668-144493568 bp, - strand  Genetic Position: Chr7, 88.92 cM
Alliance: Ccnd1tm3Pisc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:156591
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsFLAG and HA tags were inserted at the N terminus, downstream of the initiator ATG within the first exon and a neo selection cassette flanked by loxP sites was inserted within the first intron by homologous recombination. (J:156591)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccnd1 Mutation:  22 strains or lines available
References
Original:  J:156591 Bienvenu F, et al., Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature. 2010 Jan 21;463(7279):374-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory