Ccnd1^tm4Pisc
Targeted Allele Detail

Summary

• Symbol: Ccnd1^tm4Pisc
• Name: cyclin D1; targeted mutation 4, Piotr Sicinski
• MGI ID: MGI:4421801
• Synonyms: Ccnd^Ctag
• Gene: Ccnd1 Location: Chr7:144483668-144493568 bp, - strand Genetic Position: Chr7, 88.92 cM
• Alliance: Ccnd1^tm4Pisc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:156591
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: FLAG and HA tags were inserted at the C terminus, immediately upstream of the STOP (TGA) within the fifth exon and a hygro selection cassette flanked by loxP sites was inserted within the fourth intron by homologous recombination. (J:156591)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccnd1 Mutation: 22 strains or lines available

References

• Original: J:156591 Bienvenu F, et al., Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature. 2010 Jan 21;463(7279):374-8
• All: 1 reference(s)