Tlr13^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Tlr13^m1Btlr
• Name: toll-like receptor 13; mutation 1, Bruce Beutler
• MGI ID: MGI:4422095
• Synonyms: Tlr13rev1
• Gene: Tlr13 Location: ChrX:105186881-105204099 bp, + strand Genetic Position: ChrX, 47.36 cM
• Alliance: Tlr13^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation was discovered in a gene-specific sequence screen of G1 progeny of an ENU-mutagenized male mouse. It comprises an A to G transition at position 898 of the transcript (GenBank Accession 156849) that is predicted to result in replacement of aspartic acid by glycine at amino acid position 240 of the receptor protein (D240G), in the sixth leucine-rich repeat. (J:156849)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tlr13 Mutation: 6 strains or lines available

References

• Original: J:156849 Berger M, et al., An ENU-induced mutation in Tlr13. MGI Direct Data Submission. 2010
• All: 1 reference(s)