Epha4^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Epha4^m1Btlr
• Name: Eph receptor A4; mutation 1, Bruce Beutler
• MGI ID: MGI:4422099
• Synonyms: frog
• Gene: Epha4 Location: Chr1:77343822-77491725 bp, - strand Genetic Position: Chr1, 39.55 cM, cytoband C1-C5
• Alliance: Epha4^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation, discovered by its phenotype among progeny of an ENU mutagenized male mouse, has been identified as a T to C transition in the donor splice site of intron 6, at position 113891 of the gene (Genbank genomic region NC_000067 for linear genomic DNA sequence of Epha4). (J:156850)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Epha4 Mutation: 67 strains or lines available

References

• Original: J:156850 Milstein O, et al., Frog is a mutation of Epha4 that results in a gait defect. MGI Direct Data Submission. 2010
• All: 2 reference(s)