Tg(Csf1r-icre)1Jwp
Transgene Detail

Summary

• Symbol: Tg(Csf1r-icre)1Jwp
• Name: transgene insertion 1, Jeffrey W Pollard
• MGI ID: MGI:4429470
• Synonyms: cfms-icre, Csf1rMeriCreMer, Tg(Csf1.icre)jwp, Tg(Csf1r-iCre)jwp, tg(Csf1r-Meri-iCre- Mer)1Jwp
• Transgene: Tg(Csf1r-icre)1Jwp Location: unknown
• Alliance: Tg(Csf1r-icre)1Jwp page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Csf1r-icre)1Jwp expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Csf1r

• Mutation details: A transgenic construct was made with the icre (improved cre) sequence inserted downstream of the colony-stimulating factor-1 receptor (Csf1r) promoter. The construct was injected into FVB embryos. One of three founders transmitted the transgene to offspring and a line was established from this founder. (J:156593)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Csf1r (species not specified) Summary of all recombinase alleles driven by Csf1r. Comparative matrix view of recombinase activities

Disease models

Expression

In Mice Carrying this Mutation:

3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:156593 Deng L, et al., A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis. Am J Pathol. 2010 Feb;176(2):952-67
• All: 58 reference(s)