Zfp24^tm1.2Pop
Targeted Allele Detail

Summary

• Symbol: Zfp24^tm1.2Pop
• Name: zinc finger protein 24; targeted mutation 1.2, Brian Popko
• MGI ID: MGI:4429673
• Gene: Zfp24 Location: Chr18:24142759-24153867 bp, - strand Genetic Position: Chr18, 12.55 cM, cytoband B1
• Alliance: Zfp24^tm1.2Pop page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:156938
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were floxed with loxP sites and a neo selection cassette was added by homologous recombination. The neo cassette has been removed. Exons 2 and 3 were removed by cre-mediated recombination. (J:156938)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp24 Mutation: 23 strains or lines available

References

• Original: J:156938 Howng SY, et al., ZFP191 is required by oligodendrocytes for CNS myelination. Genes Dev. 2010 Feb 1;24(3):301-11
• All: 2 reference(s)