Tg(CAG-cre/Esr1*)1Egwa
Transgene Detail

Summary

• Symbol: Tg(CAG-cre/Esr1*)1Egwa
• Name: transgene insertion 1, Gyohei Egawa
• MGI ID: MGI:4430073
• Synonyms: CAG-MerCreMer, CAG-MerCreMer Tg, Tg(CAG-cre/Esr1)1Egwa
• Transgene: Tg(CAG-cre/Esr1*)1Egwa Location: unknown
• Alliance: Tg(CAG-cre/Esr1*)1Egwa page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(CAG-cre/Esr1*)1Egwa expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  chicken	CAG

• Mutation details: A transgenic construct encoding cre recombinase with mutated estrogen receptor ligand-binding domains (Esr1, Mer) at the N- and C-termini (MerCreMer) under control of the CAG promoter was injected into B6DF1 fertilized eggs to generate CAG-MerCreMer mice. (J:157054)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:157054 Egawa G, et al., Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis. J Invest Dermatol. 2009 Oct;129(10):2386-95
• All: 5 reference(s)