Celsr1^tm1Fati
Targeted Allele Detail

Summary

• Symbol: Celsr1^tm1Fati
• Name: cadherin, EGF LAG seven-pass G-type receptor 1; targeted mutation 1, Fadel Tissir
• MGI ID: MGI:4430217
• Gene: Celsr1 Location: Chr15:85783130-85918404 bp, - strand Genetic Position: Chr15, 40.42 cM
• Alliance: Celsr1^tm1Fati page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157059
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site and a neo cassette within intron 25 and an additional loxP site within intron 29 were added by homologous recombination. (J:157059)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Celsr1 Mutation: 146 strains or lines available

References

• Original: J:157059 Ravni A, et al., Planar cell polarity cadherin Celsr1 regulates skin hair patterning in the mouse. J Invest Dermatol. 2009 Oct;129(10):2507-9
• All: 3 reference(s)