Fa2h^tm1Hama
Targeted Allele Detail

Summary

• Symbol: Fa2h^tm1Hama
• Name: fatty acid 2-hydroxylase; targeted mutation 1, Hiroko Hama
• MGI ID: MGI:4430576
• Synonyms: Fa2h^flox
• Gene: Fa2h Location: Chr8:112071770-112120453 bp, - strand Genetic Position: Chr8, 57.98 cM
• Alliance: Fa2h^tm1Hama page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171655
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted in intron 4 and an FRT flanked neo cassette and loxP site were inserted in intron 6 via homologous recombination. (J:171655)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fa2h Mutation: 24 strains or lines available

References

• Original: J:171655 Potter KA, et al., Central nervous system dysfunction in a mouse model of Fa2h deficiency. Glia. 2011 Jul;59(7):1009-21
• All: 1 reference(s)