Del(13F2rl1-F2r)1Cgh
Targeted Allele Detail

Summary

• Symbol: Del(13F2rl1-F2r)1Cgh
• Name: deletion, Chr 13, Shaun R Coughlin 1
• MGI ID: MGI:4430923
• Synonyms: F2r/F2rl1^tm1.1Cgh, Par1^-/Par2^-
• Gene: Del(13F2rl1-F2r)1Cgh Location: unknown Genetic Position: Chr13, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157446
• Parent Cell Line: RF8 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(13F2rl1-F2r)1Cgh involves 3 genes/genome features (Gm19449, F2rl1, F2r) View all
• Mutation details: This allele was created by crossing mice heterozygous for both F2r^tm2Cgh and F2rl1^tm2Cgh to mice expressing a beta actin cre. The resulting allele has the entire region from the hygro selection cassette in exon 1 of F2r^tm2Cgh through the neomycin selection cassette of F2rl1^tm2Cgh excised. LacZ remains in the hybrid exon 1 that results. (J:157446)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(13F2rl1-F2r)1Cgh Mutation: 0 strains or lines available

References

• Original: J:157446 Camerer E, et al., Local protease signaling contributes to neural tube closure in the mouse embryo. Dev Cell. 2010 Jan 19;18(1):25-38
• All: 1 reference(s)