Pld4^thss
Spontaneous Allele Detail

Summary

• Symbol: Pld4^thss
• Name: phospholipase D family member 4; thin hair with small size
• MGI ID: MGI:4431064
• Gene: Pld4 Location: Chr12:112727089-112735420 bp, + strand Genetic Position: Chr12, 61.2 cM
• Alliance: Pld4^thss page

Smaller body size of the Pld4^thss/Pld4^thss mouse (upper left) cmpared to a heterozygote (lower right) at 20 days of age

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: BALB/cJ-Cst6^ichq/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This spontaneous mutation is a G-to-T transition at position 112,763,421 (GRCm38) resulting in a premature stop codon at glycine residue 46 (p.G46*). (J:179503, J:222308)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pld4 Mutation: 26 strains or lines available

References

• Original: J:171492 Harris B, et al., Thin hair with small size (thss) is a new recessive hair mutation on Chromosome 12. MGI Direct Data Submission. 2011
• All: 4 reference(s)