Tg(Tek-tTA)1Rwng
Transgene Detail

Summary

• Symbol: Tg(Tek-tTA)1Rwng
• Name: transgene insertion 1, Rong Wang
• MGI ID: MGI:4431194
• Synonyms: Tie2-tTA
• Transgene: Tg(Tek-tTA)1Rwng Location: unknown
• Alliance: Tg(Tek-tTA)1Rwng page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The tetracycline transactivator (tTA) was inserted between the 2.1 kb Tek promoter and the 10kb Tek enhancer. This transgene expresses tTA in endothelial cells. (J:99859)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:99859 Carlson TR, et al., Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9884-9
• All: 10 reference(s)