Arvcftm1a(EUCOMM)Wtsi
Targeted Allele Detail
|
Symbol: |
Arvcftm1a(EUCOMM)Wtsi |
Name: |
armadillo repeat gene deleted in velocardiofacial syndrome; targeted mutation 1a, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:4433370 |
Gene: |
Arvcf Location: Chr16:18166046-18225826 bp, + strand Genetic Position: Chr16, 11.37 cM
|
Alliance: |
Arvcftm1a(EUCOMM)Wtsi page
|
IMPC: |
Arvcf gene page |
|
Mutant Cell Lines: |
EPD0102_1_A04, EPD0102_1_B04, EPD0102_1_B05, EPD0102_1_D06, EPD0102_1_E04, EPD0102_1_E06, EPD0102_1_F04, EPD0102_1_F05, EPD0102_1_G05 |
Germline Transmission: |
Earliest citation of germline transmission:
J:165965
|
Parent Cell Line: |
JM8.F6 (ES Cell)
|
Strain of Origin: |
C57BL/6N
|
Project Collection: |
EUCOMM
|
|
Allele Type: |
|
Targeted (Conditional ready, Null/knockout, Reporter) |
Mutation: |
|
Insertion
Vector: L1L2_gt0
|
|
|
Mutation details: The L1L2_gt0 cassette was inserted at position 18214400 of Chromosome 16 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 18217341. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:155845, J:173534)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
|
Original: |
J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010; |
All: |
3 reference(s) |
|