Ffar2^tm2Lex
Targeted Allele Detail

Summary

• Symbol: Ffar2^tm2Lex
• Name: free fatty acid receptor 2; targeted mutation 2, Lexicon Genetics
• MGI ID: MGI:4436772
• Gene: Ffar2 Location: Chr7:30517778-30523200 bp, - strand Genetic Position: Chr7, 19.25 cM
• Alliance: Ffar2^tm2Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157383
• Parent Cell Line: Lex-2 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding sequence, exon 3, was replaced by a LacZ/Neo selection cassette. Absence of transcript and protein were verified by RT-PCR and western blotting. (J:157383)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ffar2 Mutation: 25 strains or lines available

References

• Original: J:157383 Sina C, et al., G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation. J Immunol. 2009 Dec 1;183(11):7514-22
• All: 1 reference(s)