Tg(Gnrh1-cre)35Awo
Transgene Detail

Summary

• Symbol: Tg(Gnrh1-cre)35Awo
• Name: transgene insertion 35, Andrew Wolfe
• MGI ID: MGI:4437236
• Synonyms: GnRH-CRE
• Transgene: Tg(Gnrh1-cre)35Awo Location: unknown
• Alliance: Tg(Gnrh1-cre)35Awo page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Gnrh1-cre)35Awo expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gnrh1 (MGI:95789)

• Mutation details: The transgenic construct contained a -3446/+28mGnRH promoter fragment in front of a 1.7-kb fragment containing the cre coding region, an intron derived from the SV40 t-antigen gene, and a nuclear localisation signal. Seven founder lines were generated and founder line 35 was chosen for further study. (J:157600)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gnrh1 (mouse) Summary of all recombinase alleles driven by Gnrh1. Comparative matrix view of recombinase activities Alliance mouse Gnrh1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:157600 Wolfe A, et al., Temporal and spatial regulation of CRE recombinase expression in gonadotrophin-releasing hormone neurones in the mouse. J Neuroendocrinol. 2008 Jul;20(7):909-16
• All: 13 reference(s)