Pilrb1^tm1Pgh
Targeted Allele Detail

Summary

• Symbol: Pilrb1^tm1Pgh
• Name: paired immunoglobin-like type 2 receptor beta 1; targeted mutation 1, Paul G Heyworth
• MGI ID: MGI:4437413
• Gene: Pilrb1 Location: Chr5:137850409-137856368 bp, - strand Genetic Position: Chr5, 76.82 cM
• Alliance: Pilrb1^tm1Pgh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157763
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 through 5 were replaced with an frt flanked neo cassette. The absence of transcript expression was confirmed by QT-PCR on kidney, lung, liver, heart, and spleen extracts. (J:157763)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pilrb1 Mutation: 9 strains or lines available

References

• Original: J:157763 Banerjee A, et al., Modulation of paired immunoglobulin-like type 2 receptor signaling alters the host response to Staphylococcus aureus-induced pneumonia. Infect Immun. 2010 Mar;78(3):1353-63
• All: 2 reference(s)