Tg(Myh6-Cast)1Gwd
Transgene Detail

Summary

• Symbol: Tg(Myh6-Cast)1Gwd
• Name: transgene insertion 1, Gerald W Dorn II
• MGI ID: MGI:4437429
• Synonyms: CSTN TG
• Transgene: Tg(Myh6-Cast)1Gwd Location: unknown
• Alliance: Tg(Myh6-Cast)1Gwd page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Cast)1Gwd expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cast (MGI:1098236)

• Mutation details: A transgenic vector was generated including the entire coding region of the calpastatin (Cast) gene under control of an alpha-myosin heavy chain (Myh6) promoter. One line was created with expression in the heart. (J:133797)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:133797 Galvez AS, et al., Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis. Circ Res. 2007 Apr 13;100(7):1071-8
• All: 1 reference(s)