Scpep1^tm1Jomm
Targeted Allele Detail

Summary

• Symbol: Scpep1^tm1Jomm
• Name: serine carboxypeptidase 1; targeted mutation 1, Joseph M Miano
• MGI ID: MGI:4437862
• Gene: Scpep1 Location: Chr11:88814846-88846268 bp, - strand Genetic Position: Chr11, 54.34 cM
• Alliance: Scpep1^tm1Jomm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:158052
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace exons 1-2 of the serine carboxypeptidase 1 (Scpep1) gene with a beta-galactosidase (lacZ) gene and a loxP-flanked neomycin resistance cassette. (J:158052)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Scpep1 Mutation: 62 strains or lines available

References

• Original: J:158052 Lee TH, et al., Functional characterization of a putative serine carboxypeptidase in vascular smooth muscle cells. Circ Res. 2009 Jul 31;105(3):271-8
• All: 1 reference(s)